Owen Wilson has signed on to voice the classic comic strip dog "Marmaduke" for 20th Century Fox says The Hollywood Reporter.

The story follows a family named the Winslows who move from Kansas to Orange County with their dog Marmaduke, a slobbery Great Dane who creates chaos wherever he goes.

Tim Rasmussen and Vince Di Meglio's script has Marmaduke navigating a volatile Mutts vs. Pedigrees turf war, wooing the purebred of his dreams and overcoming a fall from grace.

Judy Greer, Lee Pace and William H. Macy play the humans. Wilson joins Fergie, Emma Stone, George Lopez, Christopher Mintz-Plasse, Steve Coogan, Damon Wayans, Marlon Wayans who supply the voices to the film's various critters.

Tom Dey is directing the comedy which opens in June.